This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Neuhaus, J. M Search for Related Content PubMed Articles by Neuhaus, J. M Social Bookmarking                   What's this?

Statistical methods for longitudinal and clustered designs with binary responses

Department of Epidemiology and Biostatistics, University of California

Dependent binary response data arise frequently in practice due to repeated measurements in longitudi nal studies or to subsampling primary sampling units as in fields such as teratology and ophthalmology. Several classes of approaches have recently been proposed to analyse such repeated binary outcome data. The different classes of approaches measure different effects of covariates on binary responses and address different statistical questions. This article compares the different classes of approaches in terms of parameter interpretation and magnitude, standard errors of model parameters and Wald tests for covariate effects. The results help to clarify the substantive questions which data analysts can address with each approach, as well as why the covariate effects measured by different approaches may be different. Finally, I will provide guidelines to the advantages and disadvantages of alternative approaches for analysing dependent binary responses. Simulations and example data illustrate these findings.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				C. E. Bishop, D. B. Weinberg, W. Leutz, A. Dossa, S. G. Pfefferle, and R. M. Zincavage Nursing Assistants' Job Commitment: Effect of Nursing Home Organizational Factors and Impact on Resident Well-Being Gerontologist, July 1, 2008; 48(suppl_1): 36 - 45. [Abstract] [Full Text] [PDF]

				N. H. Ogden, L. R. Lindsay, K. Hanincova, I. K. Barker, M. Bigras-Poulin, D. F. Charron, A. Heagy, C. M. Francis, C. J. O'Callaghan, I. Schwartz, et al. Role of Migratory Birds in Introduction and Range Expansion of Ixodes scapularis Ticks and of Borrelia burgdorferi and Anaplasma phagocytophilum in Canada Appl. Envir. Microbiol., March 15, 2008; 74(6): 1780 - 1790. [Abstract] [Full Text] [PDF]