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Statistical Methods in Medical Research
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Analysis of a Bayesian repeated measures model for detecting differences in GP prescribing habits

Jabu S Sithole

MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK, j.sithole{at}ihr.mrc.ac.uk

Peter W Jones

Mathematics Department, Keele University, Stoke on Trent, UK

A linear mixed model is used to detect a change, if any, in the prescribing habits in the UK at the general practice (family medicine) level due to an educational intervention given repeated measures data before and after the intervention and a control group. Inferences are corrected for general practice size and fundholding status. The estimates of the model parameters are obtained using Bayesian inference by applying Gibbs sampling. We develop three different priors for the parameters of the model. These three priors correspond to ‘sceptical,’ ‘reference’ and ‘enthusiastic’ priors in terms of the opinion about the treatment effects that they represent. We compare the results obtained by using these three priors for the parameters in the random effects model.

Statistical Methods in Medical Research, Vol. 12, No. 6, 475-487 (2003)
DOI: 10.1191/0962280203sm320ra


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