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This version was published on April 1, 2008
Statistical Methods in Medical Research, Vol. 17, No. 2, 171-189 (2008)
DOI: 10.1177/0962280206075525
© 2008 SAGE Publications

A Bayesian approach to assess interaction between known risk factors: the risk of lung cancer from exposure to asbestos and smoking

D. Wraith

School of Mathematical Sciences, Queensland University of Technology, Australia, d.wraith{at}qut.edu.au

K. Mengersen

School of Mathematical Sciences, Queensland University of Technology, Australia

We review the literature on the combined effect of asbestos exposure and smoking on lung cancer, and explore a Bayesian approach to assess evidence of interaction. Previous approaches have focussed on separate tests for an additive or multiplicative relation. We extend these approaches by exploring the strength of evidence for either relation using approaches which allow the data to choose between both models. We then compare the different approaches.


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