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Statistical Methods in Medical Research
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Statistical methods in neuroimaging with particular application to emission tomography

JH McColl

Department of Statistics, University of Glasgow, Glasgow

AP Holmes

Department of Statistics, University of Glasgow, Glasgow

I. Ford

Department of Statistics, University of Glasgow, Glasgow

We review statistical methods being applied in four key areas connected with PET and SPECT neuroimaging: (i) image reconstruction (briefly); (ii) tracer-kinetic, or compartmental, modelling; (iii) inference from region-of-interest data; (iv) inference at the pixel or voxel level. Under the last heading, we pay particular attention to the analysis of data from serial scans. We conclude by identifying some topics for future statistical research.

Statistical Methods in Medical Research, Vol. 3, No. 1, 63-86 (1994)
DOI: 10.1177/096228029400300105


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