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Statistical Methods in Medical Research
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The analysis of binary and categorical data from crossover trials

MG Kenward

Rothamsted Experimental Station, Harpenden, UK

B. Jones

Institute of Mathematics and Statistics, Canterbury, UK

A review is presented of methods for the analysis of discrete data from crossover trials. The definition and interpretation of the model for the data is used as a central theme. Distinctions are drawn between different types of model, particularly marginal and subject specific. It is seen how much recent methodology for analysing correlated categorical data can be applied successfully to the crossover setting. The current accessibility of each method is considered and the different approaches are illustrated and compared using two examples.

Statistical Methods in Medical Research, Vol. 3, No. 4, 325-344 (1994)
DOI: 10.1177/096228029400300403
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